Nucleo-cytoplasmic shuttling of APC can maximize \(\beta\)-catenin/TCF concentration

DOI10.1016/j.jtbi.2011.03.018zbMath1397.92301OpenAlexW1997840392WikidataQ51585573 ScholiaQ51585573MaRDI QIDQ1783495

Katja Rateitschak, Olaf Wolkenhauer, Yvonne Schmitz

Publication date: 21 September 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2011.03.018

zbMATH Keywords

mathematical modelintracellular transportsteady state analysisretentionWnt pathway

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Cell biology (92C37)

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Cites Work

• Unnamed Item
• Approximations and their consequences for dynamic modelling of signal transduction pathways
• Elucidating the interactions between the adhesive and transcriptional functions of \(\beta\)-catenin in normal and cancerous cells
• A multiple timescale analysis of a mathematical model of the Wnt/\(\beta\)-catenin signalling pathway

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