On an unbiased and consistent estimator for mutation rates

DOI10.1016/j.jtbi.2012.01.029zbMath1397.92464OpenAlexW1973515108WikidataQ51425269 ScholiaQ51425269MaRDI QIDQ1784260

Brittany A. Niccum, Roby Poteau, Glen E. Hamman, Richard R. Sinden, Jan C. Varada, Jewgeni H. Dshalalow

Publication date: 26 September 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2012.01.029

zbMATH Keywords

stochastic analysismutagenesisLuria-Delbrück fluctuation modelspontaneous mutation

Mathematics Subject Classification ID

Problems related to evolution (92D15) Applications of branching processes (60J85) Applications of stochastic analysis (to PDEs, etc.) (60H30) Genetics and epigenetics (92D10)

Related Items (5)

Cellular replication limits in the Luria-Delbrück mutation model ⋮ Toward a unique definition of the mutation rate ⋮ Fast maximum likelihood estimation of mutation rates using a birth-death process ⋮ Accumulation of neutral mutations in growing cell colonies with competition ⋮ The Luria-Delbrück protocol is still the most practical

Cites Work

• Unnamed Item
• A stochastic model for estimation of mutation rates in multiple-replication proliferation processes
• Progress of a half century in the study of the Luria-Delbrück distribution
• Analysis of the Luria–Delbrück distribution using discrete convolution powers
• Branching processes in biology

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