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Modeling interleukin-2-based immunotherapy in AIDS pathogenesis

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Publication:1790721
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DOI10.1016/j.jtbi.2013.06.019zbMath1397.92334OpenAlexW2028160443WikidataQ42287652 ScholiaQ42287652MaRDI QIDQ1790721

Darci Odloak, Marcel Joly

Publication date: 4 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2013.06.019


zbMATH Keywords

HIVimmunotherapyimmune systemIL-2T-lymphocyte


Mathematics Subject Classification ID

Medical applications (general) (92C50) Medical epidemiology (92C60)



Uses Software

  • Matlab
  • ode23
  • ode45
  • Ode15s
  • ode113
  • ode23s
  • MATLAB ODE suite


Cites Work

  • Evolutionary game theoretic strategy for optimal drug delivery to influence selection pressure in treatment of HIV-1
  • A model of primary HIV-1 infection
  • Host immune responses that promote initial HIV spread
  • Dynamics of HIV infection of CD4\(^ +\) T cells
  • A model of HIV-1 pathogenesis that includes an intracellular delay
  • CXCR4 and CCR5 regulation and expression patterns on T- and monocyte--macrophage cell lineages: Implications for susceptibility to infection by HIV-1
  • The MATLAB ODE Suite
  • Drug concentration heterogeneity facilitates the evolution of drug resistance
  • Mathematical Analysis of HIV-1 Dynamics in Vivo
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