In silico docking reveals possible riluzole binding sites on Nav1.6 sodium channel: implications for amyotrophic lateral sclerosis therapy

DOI10.1016/j.jtbi.2012.09.004zbMath1397.92366OpenAlexW2008625105WikidataQ45735872 ScholiaQ45735872MaRDI QIDQ1790872

Francisco Capani, Janneth Gonzalez, George E. Barreto, Omar Sierra Bello

Publication date: 4 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2012.09.004

zbMATH Keywords

riluzoleamyotrophic lateral sclerosisGLN 1799Nav1.6

Mathematics Subject Classification ID

Neural biology (92C20) Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

Uses Software

• PyMOL
• ClustalW
• ESyPred3D
• PROCHECK
• PSI-BLAST
• BLAST
• Open Babel
• DrugBank
• ACD/ChemSketch

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