Neutrophil dynamics after chemotherapy and G-CSF: the role of pharmacokinetics in shaping the response

DOI10.1016/j.jtbi.2012.08.028zbMath1397.92313OpenAlexW2039689365WikidataQ51323022 ScholiaQ51323022MaRDI QIDQ1790884

Grace Brooks, Gabriel Provencher, Michael C. Mackey, Jinzhi Lei

Publication date: 4 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2012.08.028

zbMATH Keywords

resonancemathematical modelcancerrecovery rateneutropenia

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

Related Items (8)

Data-based modeling of breast cancer and optimal therapy ⋮ Characterizing chemotherapy-induced neutropenia and monocytopenia through mathematical modelling ⋮ Blood Cell Dynamics: Half of a Century of Modelling ⋮ Response of an oscillatory differential delay equation to a periodic stimulus ⋮ A mathematical model of granulopoiesis incorporating the negative feedback dynamics and kinetics of G-CSF/neutrophil binding and internalization ⋮ Understanding, treating and avoiding hematological disease: better medicine through mathematics? ⋮ Neutrophil dynamics during concurrent chemotherapy and G-CSF administration: mathematical modelling guides dose optimisation to minimise neutropenia ⋮ Bistability and State Transition of a Delay Differential Equation Model of Neutrophil Dynamics

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