A mechanistic compartmental model for total antibody uptake in tumors

DOI10.1016/J.JTBI.2012.08.034zbMath1397.92373OpenAlexW1981466338WikidataQ43066289 ScholiaQ43066289MaRDI QIDQ1790903

K. Dane Wittrup, Greg M. Thurber

Publication date: 4 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc3729444

zbMATH Keywords

permeabilityantibody localizationtumor retentiontumor targeting

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Medical applications (general) (92C50)

Related Items (1)

A mechanistic systems pharmacology modeling platform to investigate the effect of PD-L1 expression heterogeneity and dynamics on the efficacy of PD-1 and PD-L1 blocking antibodies in cancer

Cites Work

• Reoxygenation and split-dose response to radiation in a tumour model with Krogh-type vascular geometry

This page was built for publication: A mechanistic compartmental model for total antibody uptake in tumors