A mechano-regulatory bone-healing model incorporating cell-phenotype specific activity

DOI10.1016/j.jtbi.2008.01.030zbMath1401.92045OpenAlexW2162281037WikidataQ47832089 ScholiaQ47832089MaRDI QIDQ1794465

Corrinus C. van Donkelaar, Keita Ito, Rik Huiskes, Hanna Isaksson

Publication date: 15 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2008.01.030

zbMATH Keywords

finite element analysismechanobiologymechanistic modelfracture healing

Mathematics Subject Classification ID

Biomechanics (92C10) Physiology (general) (92C30) Cell biology (92C37)

Related Items (5)

Biomechanical model and numerical analysis of tissue regeneration within a porous scaffold ⋮ Theoretical evidence of osteoblast self-inhibition after activation of the genetic regulatory network controlling mineralization ⋮ Computational model of articular cartilage regeneration induced by scaffold implantation \textit{in vivo} ⋮ Numerical simulation of the tissue differentiation and corrosion process of biodegradable magnesium implants during bone fracture healing ⋮ Determining the most important cellular characteristics for fracture healing using design of experiments methods

Cites Work

• Mathematical biology. Vol. 1: An introduction.
• Influence of fracture gap size on the pattern of long bone healing: a computational study
• Mathematical modelling of the loss of tissue compression responsiveness and its role in solid tumour development

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