Drug-efficacy depends on the inhibitor type and the target position in a metabolic network -- a systematic study

DOI10.1016/J.JTBI.2007.09.027zbMath1398.92095OpenAlexW2128080665WikidataQ52922420 ScholiaQ52922420MaRDI QIDQ1794795

Heike Aßmus, Edda Klipp, Susanne Gerber, Barbara M. Bakker

Publication date: 16 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2007.09.027

zbMATH Keywords

enzyme inhibitionmetabolic control analysisflux selectivityregulation of biochemical networks

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Related Items (1)

Modelling in systems biology, neurology and pharmacy

Cites Work

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