Is maximization of molar yield in metabolic networks favoured by evolution?

DOI10.1016/j.jtbi.2007.12.008zbMath1398.92183OpenAlexW1967039865WikidataQ57320470 ScholiaQ57320470MaRDI QIDQ1794805

David A. Fell, Stefan Schuster, Thomas Pfeiffer

Publication date: 16 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2007.12.008

zbMATH Keywords

game theoryrespirationflux balance analysisfermentationmolar yieldyeast metabolism

Mathematics Subject Classification ID

Problems related to evolution (92D15) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Evolutionary games (91A22) Systems biology, networks (92C42)

Related Items (8)

Enzyme allocation problems in kinetic metabolic networks: optimal solutions are elementary flux modes ⋮ Evolutionary timeline of a modeled cell ⋮ Flux modules in metabolic networks ⋮ Cybernetic modeling of adaptive prediction of environmental changes by microorganisms ⋮ Optimal control of bacterial growth for the maximization of metabolite production ⋮ Population-level heterogeneity as a reflection of mixed strategy: a computational perspective on the Crabtree effect ⋮ Sequential activation of metabolic pathways: a dynamic optimization approach ⋮ Stoichiometric and Constraint-Based Analysis of Biochemical Reaction Networks

Cites Work

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• Stoichiometric design of metabolic networks: multifunctionality, clusters, optimization, weak and strong robustness
• Evolutionary optimization of metabolic pathways. Theoretical reconstruction of the stoichiometry of ATP and NADH producing systems
• A theoretical approach to the evolution and structural design of enzymatic networks; linear enzymatic chains, branched pathways and glycolysis of erythrocytes
• The Evolution of Cooperation
• Evolutionary Games and Population Dynamics

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