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Fitting protein-folding free energy landscape for a certain conformation to an NK fitness landscape

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Publication:1794911
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DOI10.1016/J.JTBI.2008.02.034zbMath1398.92194OpenAlexW2044498124WikidataQ51888849 ScholiaQ51888849MaRDI QIDQ1794911

Yuzuru Husimi, Takuyo Aita

Publication date: 16 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2008.02.034


zbMATH Keywords

sequence spacecanonical ensemblefitness landscape\textit{in vitro} evolutionNK model\textit{in silico} evolutionthermostability


Mathematics Subject Classification ID

Problems related to evolution (92D15) Protein sequences, DNA sequences (92D20)


Related Items (1)

Hierarchical distribution of ascending slopes, nearly neutral networks, highlands, and local optima at the \(d\)th order in an NK fitness landscape




Cites Work

  • Thermodynamical interpretation of an adaptive walk on a Mt. Fuji-type fitness landscape: Einstein relation-like formula holds in a stochastic evolution
  • Extracting characteristic properties of fitness landscape from \textit{in vitro} molecular evolution: a case study on infectivity of fd phage to \textit{E. coli}




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