Modelling the pharmacokinetics of tramadol: on the difference between CYP2D6 extensive and poor metabolizers

DOI10.1016/J.JTBI.2008.06.005zbMath1400.92223OpenAlexW2050869128WikidataQ46474177 ScholiaQ46474177MaRDI QIDQ1797587

F. Torricelli, C. Giuliani, Francesca Di Patti, Duccio Fanelli, Rasmus Søndergaard Pedersen

Publication date: 22 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2008.06.005

zbMATH Keywords

personalized medicinegenetic polymorphismsdrug metabolismO-desmethyltramadolpain therapy and experiments

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

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