Stochastic niche structure and diversity maintenance in the T cell repertoire

DOI10.1016/j.jtbi.2008.07.017zbMath1400.92174OpenAlexW2037127793WikidataQ51871488 ScholiaQ51871488MaRDI QIDQ1798192

Carmen Molina-París, Emily R. Stirk, Hugo Antonius van den Berg

Publication date: 23 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2008.07.017

zbMATH Keywords

competitionlymphocyte homeostasisbirth and death processcontinuous time Markov chainquasi-stationary probability distribution

Mathematics Subject Classification ID

Applications of branching processes (60J85) Cell biology (92C37) Applications of continuous-time Markov processes on discrete state spaces (60J28)

Related Items (8)

How many TCR clonotypes does a body maintain? ⋮ Deterministic and stochastic naive T cell population dynamics: symmetric and asymmetric cell division ⋮ About a generalized model of lymphoma ⋮ Stochastic competitive exclusion in the maintenance of the naïve T cell repertoire ⋮ Quasi-stationary and ratio of expectations distributions: a comparative study ⋮ Stochastic descriptors to study the fate and potential of naive T cell clonotypes in the periphery ⋮ Mathematical models for immunology: current state of the art and future research directions ⋮ The limiting conditional probability distribution in a stochastic model of T cell repertoire maintenance

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• Dynamics of T cell activation threshold tuning
• Coreceptor CD8-driven modulation of T cell antigen receptor specificity
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