The kientics of bivalent ligand-bivalent receptor aggregation: Ring formation and the breakdown of the equivalent site approximation

DOI10.1016/0025-5564(94)00045-2zbMath0820.92007OpenAlexW1997857545WikidataQ72126394 ScholiaQ72126394MaRDI QIDQ1804830

Byron Goldstein, Richard G. Posner, Carla Wofsy

Publication date: 14 September 1995

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(94)00045-2

zbMATH Keywords

ring formationinfinite set of coupled ordinary differential equationsbivalent ligandsaggregate size distributionbivalent receptorschain formationkinetics of aggregate formationligand concentrationsring concentrationssite approximation

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40) Physiology (general) (92C30) General theory for ordinary differential equations (34A99)

Related Items

Analysis of biochemical equilibria relevant to the immune response: finding the dissociation constants ⋮ Diffusion theory can be applied to antibodies attaching to ligand sites ⋮ Equilibrium binding of multivalent ligands to cells: Effects of cell and receptor density

Cites Work

• Analysis of a molecular signal for cell function in algebraic reactions
• Theory of equilibrium binding of a bivalent ligand to cell surface antibody: The effect of antibody heterogeneity on cross-linking
• Receptor clustering on a cell surface. I. Theory of receptor cross- linking by ligands bearing two chemically identical functional groups
• Receptor clustering on a cell surface. II. Theory of receptor cross- linking by ligands bearing two chemically distinct functional groups

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