Structural identifiability and indistinguishability of certain two- compartment models incorporating nonlinear efflux from the peripheral compartment

DOI10.1016/0025-5564(94)00023-SzbMath0821.92014OpenAlexW2138962115WikidataQ52358309 ScholiaQ52358309MaRDI QIDQ1804848

Michael J. Chappell

Publication date: 27 September 1995

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(94)00023-s

zbMATH Keywords

compartmental modelsstructural identifiabilitytwo-compartment modelHill equationsimilarity transformation approachnonlinear effluxperipheral compartmentreceptor sitessubstance input

Mathematics Subject Classification ID

System identification (93B30) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) General biology and biomathematics (92B05)

Related Items (4)

MODELING ANTIBIOTIC RESISTANCE IN PREGNANT WOMAN AND FETUS ⋮ A procedure for generating locally identifiable reparametrisations of unidentifiable nonlinear systems by the similarity transformation approach ⋮ The solution of a two-compartment model ⋮ A decomposition method for solving nonlinear systems of compartment models

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• Nonlinear control systems: An introduction
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• Global identifiability of the parameters of nonlinear systems with specified inputs: A comparison of methods
• A methodology for compartmental model indistinguishability
• On the structural output distinguishability of parametric models, and its relations with structural identifiability
• State isomorphism approach to global identifiability of nonlinear systems
• Nonlinear controllability and observability

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