Theoretical consideration of selective enrichment in in vitro selection: optimal concentration of target molecules

DOI10.1016/J.MBS.2012.07.006zbMath1316.92026OpenAlexW2021193083WikidataQ34376390 ScholiaQ34376390MaRDI QIDQ1926526

Koichi Nishigaki, Takuyo Aita, Yuzuru Husimi

Publication date: 28 December 2012

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2012.07.006

zbMATH Keywords

SELEXselection pressureevolutionary designdirected evolutionbiopanningin vitro evolution

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)

Related Items (1)

Estimation of statistical binding properties of ligand population during in vitro selection based on population dynamics theory

Cites Work

• A mathematical analysis of multiple-target SELEX
• Hierarchical distribution of ascending slopes, nearly neutral networks, highlands, and local optima at the \(d\)th order in an NK fitness landscape
• A mathematical analysis of SELEX

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