Investigations into refinements of Storey's method of multiple hypothesis testing minimising the FDR, and its application to test binomial data

DOI10.1016/J.CSDA.2012.03.026zbMath1255.62212OpenAlexW2068136149MaRDI QIDQ1927225

John H. Nixon

Publication date: 30 December 2012

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.csda.2012.03.026

zbMATH Keywords

binary datamultiple hypothesis testingfalse discovery rateFDRoptimal discovery procedure\(q\)-value

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10) Paired and multiple comparisons; multiple testing (62J15)

Uses Software

• PSI-BLAST
• BLAST
• qvality
• TGICL

Cites Work

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• Smoothing methods in statistics
• The optimal discovery procedure for large-scale significance testing, with applications to comparative microarray experiments
• The Optimal Discovery Procedure: A New Approach to Simultaneous Significance Testing
• Statistical significance for genomewide studies

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