Population genetics of neutral mutations in exponentially growing cancer cell populations

DOI10.1214/11-AAP824zbMath1377.92061arXiv1302.2742WikidataQ28705296 ScholiaQ28705296MaRDI QIDQ1948687

Richard T. Durrett

Publication date: 24 April 2013

Published in: The Annals of Applied Probability (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1302.2742

zbMATH Keywords

site frequency spectrummultitype branching processcancer modelexponentially growing population

Mathematics Subject Classification ID

Applications of branching processes (60J85) Genetics and epigenetics (92D10)

Related Items

Mutation frequencies in a birth-death branching process, Branching with selection and mutation. I: Mutant fitness of Fréchet type, A countable-type branching process model for the tug-of-war cancer cell dynamics, Statistical inference for the evolutionary history of cancer genomes, The empirical mean position of a branching Lévy process, Genetic composition of an exponentially growing cell population, Forward and backward evolutionary processes and allele frequency spectrum in a cancer cell population, An accurate approximation for the expected site frequency spectrum in a Galton-Watson process under an infinite sites mutation model, On mutations in the branching model for multitype populations, Exact site frequency spectra of neutrally evolving tumors: a transition between power laws reveals a signature of cell viability, Stochastic clonal dynamics and genetic turnover in exponentially growing populations

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