Pharmacokinetics and pharmacodynamics of therapeutic antibodies in tumors and tumor-draining lymph nodes

DOI10.3934/MBE.2021006zbMath1471.92141OpenAlexW3101973464MaRDI QIDQ1980036

Eric Salgado, Yanguang Cao

Publication date: 3 September 2021

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2021006

zbMATH Keywords

target-mediated drug disposition (TMDD)PK/PD modelingmonoclonal antibody (mAb)physiologically-based pharmacokinetic (PBPK) modelstumor-draining lymph nodes (TDLNs)

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50) Research exposition (monographs, survey articles) pertaining to biology (92-02)

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Cites Work

• Lymphatic System Flows

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