Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: a mathematical approach

DOI10.3934/MBE.2021041zbMath1471.92144OpenAlexW3111610020MaRDI QIDQ1980115

Dumitru Trucu, Raluca Eftimie, Nada Almuallem

Publication date: 3 September 2021

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2021041

zbMATH Keywords

mathematical modelasymptotic dynamicsbreast cancer cellsM1 macrophagesM2 macrophagesvesicular stomatitis virus (VSV)

Mathematics Subject Classification ID

Medical applications (general) (92C50) Qualitative investigation and simulation of ordinary differential equation models (34C60)

Related Items (7)

A mathematical model for the role of macrophages in the persistence and elimination of oncolytic viruses ⋮ Mathematical modeling and analysis of CD200-CD200R in cancer treatment ⋮ Mathematical investigation of the role of re-polarisation of M2 in cancer therapy ⋮ Mathematical investigation of innate immune responses to lung cancer: the role of macrophages with mixed phenotypes ⋮ Natural killer cells recruitment in oncolytic virotherapy: a mathematical model ⋮ A combination therapy of oncolytic viruses and chimeric antigen receptor T cells: a mathematical model proof-of-concept ⋮ A hybrid discrete-continuum modelling approach to explore the impact of T-cell infiltration on anti-tumour immune response

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