Dynamic behavior of the p53-Mdm2 core module under the action of drug Nutlin and dual delays

DOI10.3934/MBE.2021173zbMath1471.92132OpenAlexW3156879086MaRDI QIDQ1984088

Fang Yan, Haihong Liu, Juenu Yang

Publication date: 13 September 2021

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2021173

zbMATH Keywords

Hopf bifurcationtime delaysdrug Nutlinp53 signal pathway

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Cites Work

• Stochastic stability of Markovian jumping genetic regulatory networks with mixed time delays
• Time-delay systems: an overview of some recent advances and open problems.
• On p53 revival using system oriented drug dosage design
• Dynamical behaviors for a competition and cooperation model of enterprises with two delays
• Stability analysis and controller synthesis for discrete-time delayed fuzzy systems via small gain theorem

This page was built for publication: Dynamic behavior of the p53-Mdm2 core module under the action of drug Nutlin and dual delays