The interplay of biochemical and biomechanical degeneration in Alzheimer's disease

DOI10.1016/j.cma.2019.04.028zbMath1441.74132OpenAlexW2946130944WikidataQ127892796 ScholiaQ127892796MaRDI QIDQ1988050

A. Schäfer, J. Weickenmeier, Ellen Kuhl

Publication date: 16 April 2020

Published in: Computer Methods in Applied Mechanics and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.cma.2019.04.028

zbMATH Keywords

finite element analysisFisher-Kolmogorov equationAlzheimer's diseaseneuromechanics

Mathematics Subject Classification ID

Finite element methods applied to problems in solid mechanics (74S05) Medical applications (general) (92C50) Biomechanical solid mechanics (74L15)

Related Items (5)

A local domain boundary element method for solving the nonlinear Fisher KPP diffusion-reaction equation ⋮ Discontinuous Galerkin methods for Fisher-Kolmogorov equation with application to \(\alpha\)-synuclein spreading in Parkinson's disease ⋮ Insights into the microstructural origin of brain viscoelasticity. Prospects for microstructure-informed constitutive modeling ⋮ A mathematical model demonstrating the role of interstitial fluid flow on the clearance and accumulation of amyloid \(\beta\) in the brain ⋮ The amyloid cascade hypothesis and Alzheimer’s disease: A mathematical model

Uses Software

• Gmsh
• ParaView

Cites Work

• Gmsh: A 3-D finite element mesh generator with built-in pre- and post-processing facilities

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