Modeling cell dynamics in colon and intestinal crypts: the significance of central stem cells in tumorigenesis

DOI10.1007/s11538-018-0457-8zbMath1400.92074OpenAlexW2828057049WikidataQ89440708 ScholiaQ89440708MaRDI QIDQ1990141

Ali Mahdipour-Shirayeh, Leili Shahriyari

Publication date: 24 October 2018

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-018-0457-8

zbMATH Keywords

cancercell migrationfixation probabilitystem cell nichebi-compartmental stochastic modelcentral and border stem cells

Mathematics Subject Classification ID

Cell biology (92C37) Cell movement (chemotaxis, etc.) (92C17)

Cites Work

• Spatial Moran models. II: Cancer initiation in spatially structured tissue
• A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt
• Mathematical modeling of monoclonal conversion in the colonic crypt
• A nonlinear mathematical model of cell turnover, differentiation and tumorigenesis in the intestinal crypt
• Dynamics of Cancer

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