Estimation of the HIV-1 backward mutation rate from transmitted drug-resistant strains

DOI10.1016/J.TPB.2016.08.001zbMath1367.92076OpenAlexW2507502024WikidataQ37447287 ScholiaQ37447287MaRDI QIDQ2011533

Joseph Y. T. Mugisha, John M. Kitayimbwa, Roberto A. Saenz

Publication date: 4 August 2017

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.tpb.2016.08.001

zbMATH Keywords

HIV-1within-host modelvirus mutationsKaplan-Meier estimatesbackward mutation rate

Mathematics Subject Classification ID

Epidemiology (92D30) Problems related to evolution (92D15) Genetics and epigenetics (92D10)

Related Items (2)

Characterization of differential susceptibility and differential infectivity epidemic models ⋮ Dynamic analysis of conversion from a drug-sensitivity strain to a drug-resistant strain

Cites Work

• The role of backward mutations on the within-host dynamics of HIV-1
• Monte Carlo estimates of natural variation in HIV infection
• Dynamics of HIV infection of CD4\(^ +\) T cells
• Emergence of HIV-1 drug resistance during antiretroviral treatment
• Production of resistant HIV mutants during antiretroviral therapy

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