A semi-mechanistic integrated toxicokinetic-toxicodynamic (TK/TD) model for arsenic(III) in hepatocytes

DOI10.1016/J.JTBI.2012.09.019zbMath1368.92075OpenAlexW2016601958WikidataQ39764257 ScholiaQ39764257MaRDI QIDQ2013276

Ah-Ng Tony Kong, Panos G. Georgopoulos, Spyros K. Stamatelos, Ioannis P. Androulakis

Publication date: 17 August 2017

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2012.09.019

zbMATH Keywords

arsenicanti-oxidant responsehuman hepatocytesindirect response modelingNrf2

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)

Cites Work

• Mechanistic simulations of inflammation: current state and future prospects
• A model of the cell-autonomous mammalian circadian clock

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