A bioequivalence test by the direct comparison of concentration-versus-time curves using local polynomial smoothers

DOI10.1155/2016/4680642zbMath1423.92119OpenAlexW2560482626WikidataQ37512945 ScholiaQ37512945MaRDI QIDQ2013948

Dana Orange, Jingkai Gu, Suyan Tian, Mayte Suárez-Fariñas, Howard H. Chang

Publication date: 10 August 2017

Published in: Computational \& Mathematical Methods in Medicine (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1155/2016/4680642

zbMATH Keywords

local polynomial smootherspharmacokinetic parametersbioequivalence test

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Parametric hypothesis testing (62F03) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50)

Uses Software

• DEseq

Cites Work

• Unnamed Item
• Longitudinal data analysis using generalized linear models
• Variable bandwidth and local linear regression smoothers
• Bootstrap methods: another look at the jackknife
• Permutation, parametric and bootstrap tests of hypotheses.
• Bandwidth selection: Classical or plug-in?
• Robust Locally Weighted Regression and Smoothing Scatterplots
• Statistical tests for multivariate bioequivalence