A mathematical analysis of rebound in a target-mediated drug disposition model. II. With feedback

DOI10.1007/s00285-016-1073-6zbMath1397.92269OpenAlexW4240567946WikidataQ41026450 ScholiaQ41026450MaRDI QIDQ2014347

Balaji M. Agoram, Gianne Derks, Piet H. van der Graaf, Philip J. Aston

Publication date: 11 August 2017

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-016-1073-6

zbMATH Keywords

feedbackpharmacokineticspharmacodynamicssystems pharmacologyantibodyreceptor rebound

Mathematics Subject Classification ID

Feedback control (93B52) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50) Inertial manifolds and other invariant attracting sets of infinite-dimensional dissipative dynamical systems (37L25)

Related Items (1)

A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback

Cites Work

• Dynamics of target-mediated drug disposition: how a drug reaches its target
• Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting \textit{in vivo} potency
• Geometric singular perturbation theory in biological practice
• A mathematical analysis of rebound in a target-mediated drug disposition model. I: Without feedback
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