On the role of the objective in the optimization of compartmental models for biomedical therapies
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Publication:2025280
DOI10.1007/s10957-020-01754-2zbMath1462.49078OpenAlexW3090351343WikidataQ100433907 ScholiaQ100433907MaRDI QIDQ2025280
Heinz Schättler, Urszula Łedzewicz-Kowalewska
Publication date: 11 May 2021
Published in: Journal of Optimization Theory and Applications (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1007/s10957-020-01754-2
optimal controlmathematical modelingpharmacometricscancer therapies\(L_1\)- and \(L_2\)-type objectives
Medical applications (general) (92C50) Optimality conditions for problems involving ordinary differential equations (49K15) Variational principles of physics (49S05)
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Probabilistically certified region of attraction of a tumor growth model with combined chemo‐ and immunotherapy ⋮ Optimal vaccination strategies for a heterogeneous population using multiple objectives: the case of \(L_1\)- and \(L_2\)-formulations ⋮ Modeling of mouse experiments suggests that optimal anti-hormonal treatment for breast cancer is diet-dependent ⋮ Optimization of additive chemotherapy combinations for an in vitro cell cycle model with constant drug exposures ⋮ Robust domain of attraction estimation for a tumor growth model
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Cites Work
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