A systematic search for switch-like behavior in type II toxin-antitoxin systems

DOI10.1007/s00285-021-01608-zzbMath1466.92061OpenAlexW3163001686WikidataQ113905525 ScholiaQ113905525MaRDI QIDQ2030267

Cody E. FitzGerald, James P. Keener

Publication date: 7 June 2021

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-021-01608-z

zbMATH Keywords

mathematical modelingresultantswitchesbistabilitysynergycross-talkresultant analysistoxin-antitoxin systemstype II toxin-antitoxin systems

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Qualitative investigation and simulation of ordinary differential equation models (34C60) Systems biology, networks (92C42)

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Cites Work

• Oscillations and bistability in the stochastic model of p53 regulation
• A molecular model for persister in \textit{E. coli}
• The PafBC-mediated response sensitizes a bistable DNA damage response in \textit{Mycobacteria}

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