On the waiting time until coordinated mutations get fixed in regulatory sequences

DOI10.1016/j.jtbi.2021.110657zbMath1466.92123OpenAlexW3134175351MaRDI QIDQ2031806

Günter Bechly, Ann Gauger, Ola G. Hössjer

Publication date: 14 June 2021

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2021.110657

zbMATH Keywords

waiting timephase-type distributionMoran modelcontinuous time Markov processbinding sitecoordinated mutationsregulatory sequence

Mathematics Subject Classification ID

Problems related to evolution (92D15) Genetics and epigenetics (92D10)

Related Items (1)

OPTIMAL CONTROL OF GENETIC DIVERSITY IN THE MORAN MODEL WITH POPULATION GROWTH

Uses Software

• EMpht

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• A waiting time problem arising from the study of multi-stage carcinogenesis
• Mathematical population genetics. I: Theoretical introduction.
• Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability
• Phase-type distribution approximations of the waiting time until coordinated mutations get fixed in a population
• Waiting for regulatory sequences to appear
• Model of effectively neutral mutations in which selective constraint is incorporated
• Probability Models for DNA Sequence Evolution
• The application of diffusion theory to two population genetic models of Moran

This page was built for publication: On the waiting time until coordinated mutations get fixed in regulatory sequences