Mathematical investigation of innate immune responses to lung cancer: the role of macrophages with mixed phenotypes

DOI10.1016/j.jtbi.2021.110739zbMath1466.92031OpenAlexW3158434443WikidataQ113869631 ScholiaQ113869631MaRDI QIDQ2031833

Charlotte Barelle, Raluca Eftimie

Publication date: 14 June 2021

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2021.110739

zbMATH Keywords

mathematical modellingM1 and M2 macrophagesmacrophages with mixed phenotypesnon-small cell lung cancer

Mathematics Subject Classification ID

Pathology, pathophysiology (92C32)

Related Items (4)

Mathematical investigation into the role of macrophage heterogeneity on the temporal and spatio-temporal dynamics of non-small cell lung cancers ⋮ Macrophage phenotype transitions in a stochastic gene-regulatory network model ⋮ Mathematical investigation of the role of re-polarisation of M2 in cancer therapy ⋮ Role of senescent tumor cells in building a cytokine shield in the tumor microenvironment: mathematical modeling

Cites Work

• The re-polarisation of M2 and M1 macrophages and its role on cancer outcomes
• Quantifying T lymphocyte turnover
• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: a mathematical approach
• Investigation into the role of macrophages heterogeneity on solid tumour aggregations
• Modelling and investigation of the \(\mathrm{CD}4^+\) T cells -- macrophages paradox in melanoma immunotherapies
• A mathematical model for pancreatic cancer growth and treatments
• Sensitivity and Uncertainty Analysis of Complex Models of Disease Transmission: An HIV Model, as an Example

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