Modelling the interplay between the CD \(4^+\)/CD \(8^+\) t-cell ratio and the expression of MHC-i in tumours

DOI10.1007/S00285-021-01622-1zbMath1471.92095OpenAlexW3171274871WikidataQ113905509 ScholiaQ113905509MaRDI QIDQ2037063

Alexander Mozeika, Christian John Hurry, Alessia Annibale

Publication date: 30 June 2021

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-021-01622-1

zbMATH Keywords

statistical mechanicsimmunologyCD4/CD8 ratioMHC-i

Mathematics Subject Classification ID

Time-dependent statistical mechanics (dynamic and nonequilibrium) (82C99) Cell biology (92C37) Pathology, pathophysiology (92C32)

Cites Work

• Thermodynamical analysis of the dynamics of tumor interaction with the host immune system
• Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis
• Stochastic effects and bistability in T cell receptor signaling
• Immune networks: multi-tasking capabilities at medium load
• The role of idiotypic interactions in the adaptive immune system: a belief-propagation approach
• The role of the T-helper/T-suppressor ratio in the adaptive immune response: a dynamical model

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