Debiased inverse-variance weighted estimator in two-sample summary-data Mendelian randomization

DOI10.1214/20-AOS2027zbMath1486.62292arXiv1911.09802OpenAlexW3203511452MaRDI QIDQ2054477

Jun Shao, Ting Ye, Hyunseung Kang

Publication date: 3 December 2021

Published in: The Annals of Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1911.09802

zbMATH Keywords

causal inferenceMendelian randomizationmany weak instrumentsinverse variance weighted estimatorsummary data

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (3)

Breaking the winner's curse in Mendelian randomization: rerandomized inverse variance weighted estimator ⋮ A Novel Penalized Inverse-Variance Weighted Estimator for Mendelian Randomization with Applications to COVID-19 Outcomes ⋮ Mendelian Randomization Mixed-Scale Treatment Effect Robust Identification and Estimation for Causal Inference

Uses Software

• MendelianRandomization

Cites Work

• Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score
• Instrumental Variables Regression with Weak Instruments
• Consistent Estimation with a Large Number of Weak Instruments
• Mendelian randomization as an instrumental variable approach to causal inference

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