A phase I-II basket trial design to optimize dose-schedule regimes based on delayed outcomes

DOI10.1214/20-BA1205zbMath1493.62129OpenAlexW3013238781MaRDI QIDQ2057378

Ruitao Lin, Ying Yuan, Peter F. Thall

Publication date: 6 December 2021

Published in: Bayesian Analysis (Search for Journal in Brave)

Full work available at URL: https://projecteuclid.org/euclid.ba/1585360929

zbMATH Keywords

missing dataBayesian designoptimal treatment regimeadaptive randomizationbasket trialphase I-II clinical trial

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian inference (62F15) Sequential statistical design (62L05) Missing data (62D10)

Related Items (1)

Categories, components, and techniques in a modular construction of basket trials for application and further research

Uses Software

• R2jags

Cites Work

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• Analysis of multivariate probit models
• Sequential Designs for Phase I Clinical Trials with Late‐Onset Toxicities
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• Bayesian Analysis of Binary and Polychotomous Response Data
• Bayesian Dose-Finding in Two Treatment Cycles Based on the Joint Utility of Efficacy and Toxicity
• Prior distributions for variance parameters in hierarchical models (Comment on article by Browne and Draper)

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