VCSEL: prioritizing SNP-set by penalized variance component selection

DOI10.1214/21-AOAS1491zbMath1498.62230OpenAlexW4200538825MaRDI QIDQ2078274

Yanyan Li

Publication date: 28 February 2022

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1214/21-aoas1491

zbMATH Keywords

variance components modelrare variantsgroup selectionrestricted maximum likelihood (REML)penalized estimationnonconvex penaltiesmajorization-minimization (MM)multiple phenotypes

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Estimation in multivariate analysis (62H12) Ridge regression; shrinkage estimators (Lasso) (62J07) Linear regression; mixed models (62J05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Analysis of variance and covariance (ANOVA) (62J10)

Uses Software

• Julia
• SnpEff

Cites Work

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• Inductive Logic Programming
• Recovery of inter-block information when block sizes are unequal

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