Optimal control model of tumor treatment in the context of cancer stem cell

DOI10.3934/MBE.2022214zbMath1501.92045OpenAlexW4224282793MaRDI QIDQ2086840

Ghassen Haddad, Amira Kebir, Slimane Ben Miled, Nadia Raissi, Amira Bouhali

Publication date: 26 October 2022

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.3934/mbe.2022214

zbMATH Keywords

Pontryagin's maximum principleoptimal control theorycancer stem cellcancer dynamicscytotoxic treatment

Mathematics Subject Classification ID

Medical applications (general) (92C50) Existence theories for optimal control problems involving ordinary differential equations (49J15) Cell biology (92C37)

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Cites Work

• \textit{BCG} and \(IL-2\) model for bladder cancer treatment with fast and slow dynamics based on SPVF method -- stability analysis
• Mathematical modelling of cancer stem cell-targeted immunotherapy
• Mathematical model of adult stem cell regeneration with cross-talk between genetic and epigenetic regulation

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