Immune response model fitting to \(\mathrm{CD4^+}\) \(\mathrm{T}\) cell data in \textit{lymphocytic choriomeningitis virus} LCMV infection

DOI10.1007/978-3-030-78163-7_1zbMath1500.92018OpenAlexW3203770284MaRDI QIDQ2089447

Bruno M. P. M Oliveira, Atefeh Afsar, Filipe Martins, Alberto A. Pinto

Publication date: 22 October 2022

Full work available at URL: https://doi.org/10.1007/978-3-030-78163-7_1

zbMATH Keywords

residualsT cellsantigenic stimulationfitsepitope gp61epitope NP309regulatory T cells (Tregs)\textit{lymphocytic choriomeningitis virus} (LCMV)

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Pathology, pathophysiology (92C32)

Cites Work

• Autoimmunity arising from bystander proliferation of T cells in an immune response model
• Immune response dynamics
• A fit of CD4\(^+\) T cell immune response to an infection by lymphocytic choriomeningitis virus
• Tolerance and immunity in a mathematical model of T-cell mediated suppression
• Regulatory T cell adjustment of quorum growth thresholds and the control of local immune responses
• Sensibility of the quorum growth thresholds controlling local immune responses
• The role of tunable activation thresholds in the dynamics of autoimmunity
• Dynamics and Biological Thresholds
• A transcritical bifurcation in an immune response model
• Modelling the suppression of autoimmunity after pathogen infection

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