Optogenetic actuation in ChR2-transduced fibroblasts alter excitation-contraction coupling and mechano-electric feedback in coupled cardiomyocytes: a computational modeling study
DOI10.3934/mbe.2021414zbMath1501.92010OpenAlexW3204690777MaRDI QIDQ2092211
Heqing Zhan, Ling Xia, Jialun Lin, Zefeng Wang, Yuanbo Yu
Publication date: 2 November 2022
Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.3934/mbe.2021414
computational modelingmechano-electric feedbackcardiomyocyteoptogeneticsexcitation-contraction couplingfibroblast
Physiology (general) (92C30) Genetics and epigenetics (92D10) Computational methods for problems pertaining to biology (92-08)
Cites Work
- Mathematical modeling of mechanically modulated rhythm disturbances in homogeneous and heterogeneous myocardium with attenuated activity of \(\text{Na}^{+}-\text{K}^{+}\) pump
- Influence of viscosity on myocardium mechanical activity: a mathematical model
- MECHANICAL INTERACTION OF HETEROGENEOUS CARDIAC MUSCLE SEGMENTSIN SILICO: EFFECTS ONCa2+HANDLING AND ACTION POTENTIAL
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