A hybrid discrete-continuum model of immune responses to SARS-CoV-2 infection in the lung alveolar region, with a focus on interferon induced innate response

DOI10.1016/J.JTBI.2022.111293OpenAlexW4302009284MaRDI QIDQ2095409

M. Gregory Forest, Andreas C. Aristotelous, Alex W. J. Chen

Publication date: 9 November 2022

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2022.111293

zbMATH Keywords

simulationscellular automatoninnate immunityCOVID-19pneumonia

Mathematics Subject Classification ID

Biology and other natural sciences (92-XX)

Related Items (1)

Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection

Uses Software

• CSparse

Cites Work

• Chemical evolutionary games
• Direct Methods for Sparse Linear Systems
• Fingering in Stochastic Growth Models
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