A multifarious exploration of synaptic tagging and capture hypothesis in synaptic plasticity: development of an integrated mathematical model and computational experiments

DOI10.1016/j.jtbi.2022.111326zbMath1504.92012OpenAlexW4307052545WikidataQ115063348 ScholiaQ115063348MaRDI QIDQ2109268

Raheel Khan, Sandhya Samarasinghe, Don Kulasiri

Publication date: 20 December 2022

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2022.111326

zbMATH Keywords

memory allocationF-actinCaMKII-NMDAR complexlate-long term potentiationsynaptic tagging

Mathematics Subject Classification ID

Neural networks for/in biological studies, artificial life and related topics (92B20) Biochemistry, molecular biology (92C40) Memory and learning in psychology (91E40)

Uses Software

• BioNetGen

Cites Work

• Modelling bidirectional modulations in synaptic plasticity: a biochemical pathway model to understand the emergence of long term potentiation (LTP) and long term depression (LTD)
• Simulations suggest pharmacological methods for rescuing long-term potentiation

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