A minimal model of glucose-stimulated insulin secretion process explores factors responsible for the development of type 2 diabetes

DOI10.1016/J.APM.2022.03.035zbMath1503.92036OpenAlexW4226367057MaRDI QIDQ2109620

Samrat Chatterjee, Phonindra Nath Das, Abhijit Paul

Publication date: 21 December 2022

Published in: Applied Mathematical Modelling (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.apm.2022.03.035

zbMATH Keywords

sensitivity analysisinsulintype 2 diabetesinsulin resistanceglucose-stimulated insulin secretionparameter recalibration

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37) Qualitative investigation and simulation of ordinary differential equation models (34C60)

Related Items (1)

A minimal mathematical model to study insulin synthesis and secretion process

Cites Work

• Unnamed Item
• Bursting, chaos and birhythmicity originating from self-modulation of the inositol 1,4,5-trisphosphate signal in a model for intracellular Ca\(^{2+}\) oscillations
• Mathematical modelling of the intravenous glucose tolerance test
• Delay in ATP-dependent calcium inflow may affect insulin secretion from pancreatic beta-cell
• Mathematical modelling of hepatic lipid metabolism
• Mathematical models and software tools for the glucose\,-\,insulin regulatory system and diabetes: an overview
• Mathematical modeling of the glucose-insulin system: a review
• Comparison of the tangent model predictions to finite element results for the solution of the inclusion problem in viscoplasticity
• Sensitivity and Uncertainty Analysis of Complex Models of Disease Transmission: An HIV Model, as an Example

This page was built for publication: A minimal model of glucose-stimulated insulin secretion process explores factors responsible for the development of type 2 diabetes