A generalized moment-based method for estimating parameters of stochastic gene transcription

DOI10.1016/j.mbs.2022.108780zbMath1486.92125OpenAlexW4207079114MaRDI QIDQ2118516

Feng Jiao, Chunjuan Zhu, Liang Chen

Publication date: 22 March 2022

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2022.108780

zbMATH Keywords

stochastic gene transcriptionmass functionmaximum-likelihood methodmRNA distributionmoment-based method

Mathematics Subject Classification ID

Genetics and epigenetics (92D10)

Cites Work

• Unnamed Item
• Estimation of kinetic parameters of transcription from temporal single-RNA measurements
• Markovian modelling of gene product synthesis
• Distribution profiles and their dynamic transition in stochastic gene transcription
• The nonlinear dynamics and fluctuations of mRNA levels in cross-talking pathway activated transcription
• Using Gene Expression Noise to Understand Gene Regulation
• Distribution Modes and Their Corresponding Parameter Regions in Stochastic Gene Transcription
• Kinetic Foundation of the Zero-Inflated Negative Binomial Model for Single-Cell RNA Sequencing Data

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