An in silico investigation into the causes of telomere length heterogeneity and its implications for the Hayflick limit

DOI10.1016/S0022-5193(03)00229-7zbMath1464.92039OpenAlexW2089230681WikidataQ79201948 ScholiaQ79201948MaRDI QIDQ2177408

Yanyan Li

Publication date: 6 May 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/s0022-5193(03)00229-7

zbMATH Keywords

stochastic processesmodelcell cycletelomerecell agingHayflick's limit

Mathematics Subject Classification ID

Developmental biology, pattern formation (92C15) Cell biology (92C37) Genetics and epigenetics (92D10) Computational methods for problems pertaining to biology (92-08)

Related Items (4)

How could the Gompertz-Makeham law evolve ⋮ Exponentially modified Gaussian (EMG) relevance to distributions related to cell proliferation and differentiation ⋮ Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs ⋮ Random discrete competing events vs. dynamic bistable switches in cell proliferation in differentiation

Cites Work

• Random walks in random environments of a general type

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