Brownian dynamics simulation of nucleosome formation and disruption under stretching
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Publication:2186502
DOI10.1016/J.JTBI.2004.03.028zbMATH Open1447.92142arXivq-bio/0312036OpenAlexW2139750159WikidataQ52559600 ScholiaQ52559600MaRDI QIDQ2186502
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Publication date: 9 June 2020
Published in: (Search for Journal in Brave)
Abstract: Using a Brownian dynamics simulation, we numerically studied the interaction of DNA with histone and proposed an octamer-rotation model to describe the process of nucleosome formation. Nucleosome disruption under stretching was also simulated. The theoretical curves of extension versus time as well as of force versus extension are consistent with previous experimental results.
Full work available at URL: https://arxiv.org/abs/q-bio/0312036
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