T cell development in the thymus: from periodic seeding to constant output

DOI10.1016/j.jtbi.2007.07.028zbMath1453.92039OpenAlexW2081246106WikidataQ51905870 ScholiaQ51905870MaRDI QIDQ2216319

Barry D. Hughes, Anna Q. Cai, Colleen M. Witt, Kerry A. Landman

Publication date: 15 December 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2007.07.028

zbMATH Keywords

periodic oscillationsdifferentiationproliferationthymusthymocytes

Mathematics Subject Classification ID

Developmental biology, pattern formation (92C15) Cell biology (92C37)

Cites Work

• Feedback loops, reversals and nonlinearities in lymphocyte development
• Estimation of the proliferation and maturation functions in a physiologically structured model of thymocyte development
• A general mathematical method for investigating the thymic microenvironment, thymocyte development, and immunopathogeneisis
• An improved model of T cell development in the thymus and its stability analysis
• Oscillation and Chaos in Physiological Control Systems

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