Robust p53 recovery using chattering free sliding mode control and a gain-scheduled modified utkin observer

DOI10.1016/J.JTBI.2021.110914zbMath1476.92023OpenAlexW3203312175MaRDI QIDQ2243101

Syed Bilal Javed, Ali Arshad Uppal, Muhammad Rizwan Azam, Sheher Bano, Aamer Iqbal Bhatti

Publication date: 10 November 2021

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2021.110914

zbMATH Keywords

sliding mode controldrug deliverytargeted cancer therapycancer controldrug dosage designp53 recovery

Mathematics Subject Classification ID

Medical applications (general) (92C50) Variable structure systems (93B12) Observers (93B53)

Cites Work

• Personalized drug administration for cancer treatment using model reference adaptive control
• Chattering free full-order sliding-mode control
• Sliding modes in control and optimization. Transl. from the Russian
• The dynamics of an optimally controlled tumor model: A case study
• On p53 revival using system oriented drug dosage design
• On the development of discontinuous observers
• Optimal chemotherapy in cancer treatment: state dependent Riccati equation control and extended Kalman filter

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