Two-mutation model for carcinogenesis: Joint analysis of premalignant and malignant lesions

DOI10.1016/0025-5564(91)90032-EzbMath0724.92015OpenAlexW2058687572WikidataQ41149867 ScholiaQ41149867MaRDI QIDQ2277188

Anup Dewanji, Suresh H. Moolgavkar, E. Georg Luebeck

Publication date: 1991

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(91)90032-e

zbMATH Keywords

carcinogenesisaltered hepatic foci in rodentsgeneralization of the recessive oncogenesis hypothesisinactivation of homologous tumor suppressor genesmalignant transformationpremalignant lesions

Mathematics Subject Classification ID

Applications of branching processes (60J85) Medical applications (general) (92C50)

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Cites Work

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• A stochastic Gompertz birth-death process
• Two-event models for carcinogenesis: Incidence curves for childhood and adult tumors
• Some Stochastic Models for Small Epidemics in Large Populations
• Partial differential equations

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