Understanding the role of phenotypic switching in cancer drug resistance

DOI10.1016/j.jtbi.2020.110162zbMath1430.92036arXiv2001.07690OpenAlexW2999859696WikidataQ92738098 ScholiaQ92738098MaRDI QIDQ2297830

Subhajyoti De, Einar Bjarki Gunnarsson, Kevin Leder, Jasmine Foo

Publication date: 20 February 2020

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/2001.07690

zbMATH Keywords

mathematical modelingevolutionary dynamicsphenotypic switchingepigeneticscancer drug resistance

Mathematics Subject Classification ID

Problems related to evolution (92D15) Medical applications (general) (92C50) Genetics and epigenetics (92D10)

Related Items (4)

A continuation technique for maximum likelihood estimators in biological models ⋮ Statistical inference of the rates of cell proliferation and phenotypic switching in cancer ⋮ Cell population growth kinetics in the presence of stochastic heterogeneity of cell phenotype ⋮ Transition therapy: tackling the ecology of tumor phenotypic plasticity

Cites Work

• Bet-hedging in stochastically switching environments
• Branching Process Models of Cancer
• Unnamed Item

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