Brain energetics plays a key role in the coordination of electrophysiology, metabolism and hemodynamics: evidence from an integrated computational model

DOI10.1016/j.jtbi.2019.06.003zbMath1416.92047OpenAlexW2948102600WikidataQ92599804 ScholiaQ92599804MaRDI QIDQ2317042

Erkki Somersalo, J. Prezioso, Luca Gerardo-Giorda, G. Capo Rangel, Daniela Calvetti

Publication date: 8 August 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://hdl.handle.net/20.500.11824/988

zbMATH Keywords

hemodynamicsmetabolismelectrophysiologybrain energetics

Mathematics Subject Classification ID

Physiology (general) (92C30) Cell biology (92C37) Physiological flow (92C35)

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Cites Work

• A computational model integrating brain electrophysiology and metabolism highlights the key role of extracellular potassium and oxygen
• Estimating hemodynamic stimulus and blood vessel compliance from cerebral blood flow data
• Mathematical model for the estimation of hemodynamic and oxygenation variables by tissue spectroscopy
• Dynamic activation model for a glutamatergic neurovascular unit

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