Flexible link continual reassessment methods for trivariate binary outcome phase I/II trials
DOI10.1080/15598608.2013.772815zbMath1423.62033OpenAlexW2151600263MaRDI QIDQ2320854
Publication date: 27 August 2019
Published in: Journal of Statistical Theory and Practice (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1080/15598608.2013.772815
toxicitynonparametric link functionscontinual reassessment method (CRM)maximum tolerated dose (MTD)Bayesian adaptive methodsphase III clinical trialsurrogate efficacytrivariate binary outcome
Nonparametric regression and quantile regression (62G08) Estimation in multivariate analysis (62H12) Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian problems; characterization of Bayes procedures (62C10)
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