Properties and evaluation of the MOBIT -- a novel linkage-based test statistic and quantification method for imprinting

DOI10.1515/sagmb-2018-0025zbMath1420.92050OpenAlexW2959625869WikidataQ100388940 ScholiaQ100388940MaRDI QIDQ2325032

Konstantin Strauch, Michael P. Knapp, Markus Brugger

Publication date: 12 September 2019

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1515/sagmb-2018-0025

zbMATH Keywords

confoundinglinkage analysisgenomic imprintingMOD scoressex-specific recombination frequencies

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Genetics and epigenetics (92D10)

Uses Software

• powerpkg
• Allegro

Cites Work

• Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests Under Nonstandard Conditions
• Computer-simulation methods in human linkage analysis.
• Quantifying Genomic Imprinting in the Presence of Linkage

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